BDBM30407 5-hydroxy- 3(2H)-pyridazinone, 2::BMCL185002 Compound 1

SMILES CC(C)CCN1C(=O)C(=C(C(=N1)c2cccs2)O)C3=Nc4ccc(cc4S(=O)(=O)N3)NS(=O)(=O)C

InChI Key InChIKey=UNKTYNIAIAATDF-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30407   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30407(BMCL185002 Compound 1 | 5-hydroxy- 3(2H)-pyridazin...)
Affinity DataIC50: 10nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30407(BMCL185002 Compound 1 | 5-hydroxy- 3(2H)-pyridazin...)
Affinity DataIC50: 10nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)