BDBM303946 US10138242, Compound 32

SMILES Cn1c2c(c(n1)C(=O)NCc3cccc4c3cccc4)CN(CC2)Cc5c[nH]c6c5cccc6

InChI Key InChIKey=XJVZXIUKPNWOSD-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 303946   

LigandPNGBDBM303946(US10138242, Compound 32)
Affinity DataEC50:  2.72E+4nMAssay Description:The assay uses two types of beads: donor beads are coupled with streptavidin, and acceptor beads are coupled with an anti His-tag antibody. Upon exci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM303946(US10138242, Compound 32)
Affinity DataIC50: 4.79E+3nMAssay Description:Antitrypanosomal activity was tested on T. brucei brucei bloodstream from parasites (strain Lister 427, VATMITat 1.2). Stock solutions of compounds (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

TargetPeroxisomal membrane protein PEX14(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM303946(US10138242, Compound 32)
Affinity DataEC50:  5.11E+4nMAssay Description:Inhibition of biotinylated PEX5-derived ALSENWAQEFLA binding to human N-terminal His-tagged PEX14 (21 to 84 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed