BDBM303933 US10138242, Compound 19

SMILES OCCn1nc(C(=O)NCc2ccccc2)c2CN(Cc3c[nH]c4ccccc34)CCc12

InChI Key InChIKey=HLRVGHSWSPPTDS-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 303933   

LigandPNGBDBM303933(US10138242, Compound 19)
Affinity DataEC50:  1.18E+5nMAssay Description:The assay uses two types of beads: donor beads are coupled with streptavidin, and acceptor beads are coupled with an anti His-tag antibody. Upon exci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM303933(US10138242, Compound 19)
Affinity DataIC50: 1.52E+4nMAssay Description:Antitrypanosomal activity was tested on T. brucei brucei bloodstream from parasites (strain Lister 427, VATMITat 1.2). Stock solutions of compounds (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
Go to US Patent

TargetPeroxisomal membrane protein PEX14(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM303933(US10138242, Compound 19)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of biotinylated PEX5-derived ALSENWAQEFLA binding to human N-terminal His-tagged PEX14 (21 to 84 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed