BDBM303779 (3S)-N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-2-yl]-1- [4-(2-oxa-7- azaspiro[3.4]octan-7- ylmethyl)phenyl]-5-oxo- pyrrolidine-3- carboxamide::US10138230, Example F212

SMILES Clc1ccc(CCc2nnc(NC(=O)[C@@H]3CN(C(=O)C3)c3ccc(CN4CCC5(COC5)C4)cc3)s2)cc1

InChI Key InChIKey=LNDDLKMDRAEFQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303779   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303779((3S)-N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadi...)
Affinity DataIC50: 1nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
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Date in BDB:
3/29/2019
Entry Details
Go to US Patent