BDBM303704 N-[1-[4-(azepan-1- ylmethyl)phenyl]-5-oxo- pyrrolidin-3-yl]-5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazole-2- carboxamide::US10138230, Example F134

SMILES Clc1ccc(CCc2nnc(s2)C(=O)NC2CN(C(=O)C2)c2ccc(CN3CCCCCC3)cc2)cc1

InChI Key InChIKey=GLQOACXEEUSLPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303704   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303704(N-[1-[4-(azepan-1- ylmethyl)phenyl]-5-oxo- pyrroli...)
Affinity DataIC50: 3nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent