BDBM303699 5-[2-(4- chlorophenyl)ethyl]-N-[1- [4-(1,4-oxazepan-4- ylmethyl)phenyl]-5-oxo- pyrrolidin-3-yl]-1,3,4- thiadiazole-2- carboxamide::US10138230, Example F129

SMILES Clc1ccc(CCc2nnc(s2)C(=O)NC2CN(C(=O)C2)c2ccc(CN3CCCOCC3)cc2)cc1

InChI Key InChIKey=QMLTZSFCKADIAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303699   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303699(5-[2-(4- chlorophenyl)ethyl]-N-[1- [4-(1,4-oxazepa...)
Affinity DataIC50: 2nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
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Date in BDB:
3/29/2019
Entry Details
Go to US Patent