BDBM303687 N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-2-yl]-1- [4-[(4-methylpiperazin-1- yl)methyl]phenyl]-5-oxo- pyrrolidine-3- carboxamide::US10138230, Example F117

SMILES CN1CCN(Cc2ccc(cc2)N2CC(CC2=O)C(=O)Nc2nnc(CCc3ccc(Cl)cc3)s2)CC1

InChI Key InChIKey=KFUHYSZEQJZADD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303687   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303687(N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-...)
Affinity DataIC50: 4nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
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Date in BDB:
3/29/2019
Entry Details
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