BDBM303685 N-[5-(2- cyclopentylethyl)-1,3,4- thiadiazol-2-yl]-1-[4- [(3,3-difluoro-1- piperidyl)methyl]phenyl]- 5-oxo-pyrrolidine-3- carboxamide::US10138230, Example F115

SMILES FC1(F)CCCN(Cc2ccc(cc2)N2CC(CC2=O)C(=O)Nc2nnc(CCC3CCCC3)s2)C1

InChI Key InChIKey=UYKBTJJNIAVUDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303685   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303685(N-[5-(2- cyclopentylethyl)-1,3,4- thiadiazol-2-yl]...)
Affinity DataIC50: 3nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
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Date in BDB:
3/29/2019
Entry Details
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