BDBM303681 N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-2-yl]-1- [4- [[methyl(tetrahydropyran- 4- yl)amino]methyl]phenyl]- 5-oxo-pyrrolidine-3- carboxamide::US10138230, Example F111

SMILES CN(Cc1ccc(cc1)N1CC(CC1=O)C(=O)Nc1nnc(CCc2ccc(Cl)cc2)s1)C1CCOCC1

InChI Key InChIKey=SADLSAFSSQGHAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303681   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303681(N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-...)
Affinity DataIC50: 3nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent