BDBM303673 (3S)-1-[4-(3- azabicyclo[3.1.0]hexan- 3-ylmethyl)phenyl]-N-[5- [2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-2-yl]-5- oxo-pyrrolidine-3- carboxamide::US10138230, Example F103

SMILES [H][C@]1(CN(C(=O)C1)c1ccc(CN2CC3CC3C2)cc1)C(=O)Nc1nnc(CCc2ccc(Cl)cc2)s1

InChI Key InChIKey=UMHMRDDJMNVDSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303673   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303673((3S)-1-[4-(3- azabicyclo[3.1.0]hexan- 3-ylmethyl)p...)
Affinity DataIC50: 3nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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