BDBM30337 3-aryl isoxazole analog, 7b

SMILES CC(Cl)c1onc(c1COc1ccc(c(C)c1)-c1ccc2c(cn(C)c2c1)C(O)=O)-c1c(Cl)c[n+]([O-])cc1Cl

InChI Key InChIKey=YQQXIRGBZGCVPG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30337   

TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30337(3-aryl isoxazole analog, 7b)
Affinity DataIC50: 45nM EC50:  102nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed