BDBM303315 2-amino-8-fluoro-N-[(6- isoppropoxy-2- pyridyl)methyl]quinazoline- 4-carboxamide::US10138212, Example 78

SMILES CC(C)Oc1cccc(CNC(=O)c2nc(N)nc3c(F)cccc23)n1

InChI Key InChIKey=RIARDWCERDHTRL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303315   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM303315(2-amino-8-fluoro-N-[(6- isoppropoxy-2- pyridyl)met...)
Affinity DataKi:  1nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent