BDBM303267 2-amino-N-(6,7-dihydro- 5H-cyclopenta[b]pyridin- 7-yl)-8-methoxy- quinazoline-4- carboxamide (+ or -)::US10138212, Example 32

SMILES COc1cccc2c(nc(N)nc12)C(=O)NCC1Cc2cccnc2C1

InChI Key InChIKey=JDDLIRSRSYOMFY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303267   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM303267(2-amino-N-(6,7-dihydro- 5H-cyclopenta[b]pyridin- 7...)
Affinity DataKi:  1.80nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent