BDBM303240 US10137122, Compound 118

SMILES CC1(C)CC(=O)C2=C(C1)Nc1n[nH]c(C3CC3)c1C2(C)c1cccc(C#N)c1

InChI Key InChIKey=VAPVCGAVXYXZNZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303240   

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 303240BDBM303240(US10137122, Compound 118)
Affinity DataIC50: 100nMAssay Description:A solution of 4× inhibitor (5 μL), 4× substrate/ATP-Metal solution (5 μL), and 2× Kinase solution (10 μL) was prepared with assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 303240BDBM303240(US10137122, Compound 118)
Affinity DataIC50: 100nMAssay Description:Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substrate (Phenacetin) in the presence of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent