BDBM30311 Pyrrolo-pyrimidone, 4

SMILES COc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1

InChI Key InChIKey=SMKRVAGTVDEXFZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30311   

TargetMAP kinase-activated protein kinase 2(Human)
Novartis

LigandBDBM30311(Pyrrolo-pyrimidone, 4)Copy SMILESCopy InChI

Affinity DataIC50: 550nMpH: 7.5 T: 2°CAssay Description:For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/4/2009
Entry Details Article
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TargetMAP kinase-activated protein kinase 2(Human)
Novartis

LigandBDBM30311(Pyrrolo-pyrimidone, 4)Copy SMILESCopy InChI

Affinity DataIC50: 540nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2010
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL