BDBM302988 US9598440, 129

SMILES CC(C)(O)[C@H]1C[C@@H](Nc2nc(Nc3cccc(c3)C(N)=O)ncc2-c2nc3ccccc3s2)[C@H](O)[C@@H]1O

InChI Key InChIKey=XACPURFNAMOXLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302988   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM302988(US9598440, 129)
Affinity DataIC50: 1.40nMAssay Description:Procedure: A 20 μl reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent