BDBM302455 2-(3-Fluorophenyl)-N5- (4-(trifluoromethyl) phenyl)-6,7- dihydropyrazolo[1,5- a]pyrazine-3,5(4H)- dicarboxamide::US9598423, Example 21

SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XMOYYGJKQYQYCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302455   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302455(2-(3-Fluorophenyl)-N5- (4-(trifluoromethyl) phenyl...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302455(2-(3-Fluorophenyl)-N5- (4-(trifluoromethyl) phenyl...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent