BDBM302357 (2S)-2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl]-methoxy}propan-1-ol::US9598416, Example 3

SMILES COc1cc(C)cc2cc(sc12)-c1c(CO[C@@H](C)CO)cn2ncnc(N)c12

InChI Key InChIKey=ZZDKMIARNROCNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302357   

TargetFibroblast growth factor receptor 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302357((2S)-2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothio...)
Affinity DataIC50: 1.80nMAssay Description:Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302357((2S)-2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothio...)
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent