BDBM302068 US9598407, Compound 24

SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=HBOUMUWFMQOEBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302068   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Janssen Ireland

US Patent
LigandPNGBDBM302068(US9598407, Compound 24)
Affinity DataIC50: 1.90E+4nMAssay Description:FabI enzyme inhibition assays were carried out in half-area, 384-well microtitre plates. Compounds were evaluated in 40-μl assay mixtures contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent