BDBM302043 US9598405, 5.2

SMILES C[C@H]1C[C@@](O)(CC[C@H]1C(O)=O)c1ncc(s1)-c1cc(C)cc(Nc2cc(C)c(F)cn2)n1

InChI Key InChIKey=LCLISMCSKAWCMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302043   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM302043(US9598405, 5.2)
Affinity DataIC50: 0.580nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent