BDBM302038 US9598405, 4.5

SMILES CC(C)Oc1ccnc(Nc2cc(C)cc(n2)-c2cnc(s2)C2(O)CCC(CC2)C(O)=O)c1

InChI Key InChIKey=SMNXOMWRXYQXSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302038   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM302038(US9598405, 4.5)
Affinity DataIC50: 0.862nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent