BDBM30202 Pyrrolopyridine, 33

SMILES O=C(NC1CCCC1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1

InChI Key InChIKey=VZGXJTZKPDEJGJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30202   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

LigandBDBM30202(Pyrrolopyridine, 33)Copy SMILESCopy InChI

Affinity DataIC50: 8nMAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/5/2009
Entry Details Article
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM30202(Pyrrolopyridine, 33)Copy SMILESCopy InChI

Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/30/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL