BDBM302004 US9598405, 2.3

SMILES Cc1cc(Nc2cc(OCCCNC(=O)OC(C)(C)C)ccn2)nc(c1)-c1cnc(s1)C1(O)CCC(CC1)C(O)=O

InChI Key InChIKey=RNSWSVJUSLIWBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302004   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM302004(US9598405, 2.3)
Affinity DataIC50: 23.9nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent