BDBM302003 US9598405, 2.2

SMILES COc1ccc(Cn2cc(nn2)-c2ccnc(Nc3cc(C)cc(n3)-c3cnc(s3)C3(O)CCC(CC3)C(O)=O)c2)cc1

InChI Key InChIKey=UJGKSBUGIGRVRQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302003   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM302003(US9598405, 2.2)
Affinity DataIC50: 1.19nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent