BDBM301995 US9598405, 1.3

SMILES COC(=O)[C@H]1CC[C@@](O)(CC1(C)C)c1ncc(s1)-c1cc(C)cc(Nc2cc(ccn2)C2CC2)n1

InChI Key InChIKey=JFZIUIZRZCLZGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301995   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM301995(US9598405, 1.3)
Affinity DataIC50: 1.31nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent