BDBM301936 US9598396, Compound 11

SMILES COc1cccc(CC(C)(C#N)c2ccc3c4CCCCc4c(=O)[nH]c3c2)c1

InChI Key InChIKey=BMXUSXFYGFJVNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 301936   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301936(US9598396, Compound 11)
Affinity DataIC50: 35.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301936(US9598396, Compound 11)
Affinity DataIC50: 87.1nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent