BDBM301786 4-Phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)piperazine-1-carboxamide ::US9598387, Compound 2::US9969743, 2

SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCNC(=O)N2CCN(CC2)c2ccccc2)CC1

InChI Key InChIKey=PBUOIALTCUSCTG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 301786   

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301786(4-Phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  14.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301786(4-Phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  14.2nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301786(4-Phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  303nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301786(4-Phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  303nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
Go to US Patent