BDBM30135 alpha-sulfone piperidine hydroxamate, 1a

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCNCC1)C(=O)NO

InChI Key InChIKey=PVOQKYVUWAHQSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30135   

LigandPNGBDBM30135(alpha-sulfone piperidine hydroxamate, 1a)
Affinity DataIC50: 201nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

LigandPNGBDBM30135(alpha-sulfone piperidine hydroxamate, 1a)
Affinity DataIC50: 4.02E+3nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed