BDBM300887 (3R)-3-[6-[[3-(2- Methylphenyl)benzo[b]thiophen- 5-yl]methoxy]pyridin-3-yl] hex-4-ynoic acid::US10131648, Compound 85::US10195178, Compound 85::US9790198, Compound 85

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccccc4C)c3c2)nc1

InChI Key InChIKey=GSEDIQRMBUAZBA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300887   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300887((3R)-3-[6-[[3-(2- Methylphenyl)benzo[b]thiophen- 5...)
Affinity DataEC50:  7nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300887((3R)-3-[6-[[3-(2- Methylphenyl)benzo[b]thiophen- 5...)
Affinity DataEC50:  7nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300887((3R)-3-[6-[[3-(2- Methylphenyl)benzo[b]thiophen- 5...)
Affinity DataEC50:  7nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300887((3R)-3-[6-[[3-(2- Methylphenyl)benzo[b]thiophen- 5...)
Affinity DataEC50:  6nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent