BDBM300883 (3S)-3-(4-((3-(4- Methoxypyridin-3- yl)benzo[b]thiophen-5- yl)methoxy)phenyl)hex-4-ynoic acid::US10131648, Compound 81::US10195178, Compound 81::US9790198, Compound 81

SMILES COc1ccncc1-c1csc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc12

InChI Key InChIKey=AAAGJRIQWZJWDJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300883   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300883((3S)-3-(4-((3-(4- Methoxypyridin-3- yl)benzo[b]thi...)
Affinity DataEC50:  11nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300883((3S)-3-(4-((3-(4- Methoxypyridin-3- yl)benzo[b]thi...)
Affinity DataEC50:  11nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300883((3S)-3-(4-((3-(4- Methoxypyridin-3- yl)benzo[b]thi...)
Affinity DataEC50:  11nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent