BDBM300874 (3S)-3-(6-((3-(2-Methyl-4- ((tetrahydro-2H-pyran-4- yl)methoxy)phenyl)benzo[b] thiophen-5-yl)methoxy)pyridin-3- yl)hex-4-ynoic acid::US10131648, Compound 72::US10195178, Compound 72::US9790198, Compound 72

SMILES CC#C[C@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccc(OCC5CCOCC5)cc4C)c3c2)nc1

InChI Key InChIKey=JFGBKHGVAQMWHZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300874   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300874((3S)-3-(6-((3-(2-Methyl-4- ((tetrahydro-2H-pyran-4...)
Affinity DataEC50:  1.33E+3nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300874((3S)-3-(6-((3-(2-Methyl-4- ((tetrahydro-2H-pyran-4...)
Affinity DataEC50:  1.33E+3nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300874((3S)-3-(6-((3-(2-Methyl-4- ((tetrahydro-2H-pyran-4...)
Affinity DataEC50:  1.33E+3nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent