BDBM300864 3-(6-((3-(4-(2,3- Dihydroxypropoxy)-2- phenyl)benzo[b]thiophen- 5-yl)methoxy)pyridin-3-yl) hex-4-ynoic acid::US10131648, Compound 62::US10195178, Compound 62::US9790198, Compound 62

SMILES CC#CC(CC(O)=O)c1ccc(OCc2ccc3scc(-c4ccc(OCC(O)CO)cc4C)c3c2)nc1

InChI Key InChIKey=CVZYTWWGNQXOIJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300864   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300864(3-(6-((3-(4-(2,3- Dihydroxypropoxy)-2- phenyl)benz...)
Affinity DataEC50:  10nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300864(3-(6-((3-(4-(2,3- Dihydroxypropoxy)-2- phenyl)benz...)
Affinity DataEC50:  10nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300864(3-(6-((3-(4-(2,3- Dihydroxypropoxy)-2- phenyl)benz...)
Affinity DataEC50:  10nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent