BDBM300856 (3S)-3-[4-[([3-[4-(3-Hydroxy-3- methylbutoxy)-2- methylphenyl]-1- benzothiophen-5- yl]oxy)methyl]phenyl] hex-4-ynoic acid::US10131648, Compound 54::US10195178, Compound 54::US9790198, Compound 54

SMILES CC#C[C@@H](CC(O)=O)c1ccc(COc2ccc3scc(-c4ccc(OCCC(C)(C)O)cc4C)c3c2)cc1

InChI Key InChIKey=QZMUHKMVFANQTL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300856   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300856((3S)-3-[4-[([3-[4-(3-Hydroxy-3- methylbutoxy)-2- m...)
Affinity DataEC50:  44nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300856((3S)-3-[4-[([3-[4-(3-Hydroxy-3- methylbutoxy)-2- m...)
Affinity DataEC50:  44nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300856((3S)-3-[4-[([3-[4-(3-Hydroxy-3- methylbutoxy)-2- m...)
Affinity DataEC50:  44nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent