BDBM300854 (3S)-3-(4-((3-(2-Chloro-5- methylpyridin-4- yl)benzo[b]thiophen-5- yl)methoxy)phenyl) hex-4-ynoic acid::US10131648, Compound 52::US10195178, Compound 52::US9790198, Compound 52

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4cc(Cl)ncc4C)c3c2)cc1

InChI Key InChIKey=PIKWPCCEXPYYJT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300854   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300854((3S)-3-(4-((3-(2-Chloro-5- methylpyridin-4- yl)ben...)
Affinity DataEC50:  19nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300854((3S)-3-(4-((3-(2-Chloro-5- methylpyridin-4- yl)ben...)
Affinity DataEC50:  19nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300854((3S)-3-(4-((3-(2-Chloro-5- methylpyridin-4- yl)ben...)
Affinity DataEC50:  19nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent