BDBM300566 4-(cyclopropyloxy)-3-({[1-(4-cyclopropylpiperazin-1-yl)cyclopropyl]carbonyl}amino)-N-[6-(2-fluorophenyl)pyridin-3-yl]benzamide::US10130633, Example 136
SMILES O=C(Nc2ccc(c1ccccc1F)nc2)c7ccc(OC3CC3)c(NC(=O)C6(N5CCN(C4CC4)CC5)CC6)c7
InChI Key InChIKey=WUXIYFKQIOIKPO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 300566
Affinity DataIC50: 21.4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair