BDBM30036 cid_44142096::triazolothiadiazine, 30

SMILES FC(F)Oc1ccc(cc1OCC1CC1)C1=Nn2c(SC1)nnc2-c1ccccc1Cl

InChI Key InChIKey=LFZGKSILZCJTOF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30036   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
National Human Genome Research Institute

LigandPNGBDBM30036(cid_44142096 | triazolothiadiazine, 30)
Affinity DataIC50: 37nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM30036(cid_44142096 | triazolothiadiazine, 30)
Affinity DataEC50:  3.89E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1 R01 HL081062-01 Project Title: HTS for Identification of VLA-4 Allosteric Modulators (ML...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay