BDBM30022 triazolothiadiazine, 8

SMILES COc1ccc(OC)c(c1)-c1nnc2SCC(=Nn12)c1ccc(OC(F)F)c(OCC2CC2)c1

InChI Key InChIKey=RYEJSNBHBPXFLF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30022   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
National Human Genome Research Institute

LigandPNGBDBM30022(triazolothiadiazine, 8)
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed