BDBM299617 6-[3-(difluoro- methoxy)phenyl] pyrido[3,2-d] pyrimidin-4-amine::US9592235, Example 363::US9855269, Compound 290

SMILES Nc1ncnc2ccc(nc12)-c1cccc(OC(F)F)c1

InChI Key InChIKey=MGXSZEBSENIQSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299617   

LigandPNGBDBM299617(US9592235, Example 363 | 6-[3-(difluoro- methoxy)p...)
Affinity DataIC50: 71.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM299617(US9592235, Example 363 | 6-[3-(difluoro- methoxy)p...)
Affinity DataIC50: 71.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent