BDBM299544 N-[3-(4-amino- pyrido[3,2-d] pyrimidin- 6-yl)-5-fluoro- phenyl]-2- pyrrolidin-1-yl- acetamide::US9592235, Example 314::US9855269, Compound 163

SMILES Nc1ncnc2ccc(nc12)-c1cc(F)cc(NC(=O)CN2CCCC2)c1

InChI Key InChIKey=VHDOJOVCAVZTRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299544   

LigandPNGBDBM299544(US9592235, Example 314 | N-[3-(4-amino- pyrido[3,2...)
Affinity DataIC50: 7.25nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299544(US9592235, Example 314 | N-[3-(4-amino- pyrido[3,2...)
Affinity DataIC50: 7.25nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent