BDBM299523 6-[3-(2-pyridyl)-1- piperidyl]pyrido [3,2-d]pyrimidin- 4-amine::US9592235, Example 297::US9855269, Compound 144

SMILES Nc1ncnc2ccc(nc12)N1CCCC(C1)c1ccccn1

InChI Key InChIKey=GFRVXOFCGOCMEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299523   

LigandPNGBDBM299523(US9592235, Example 297 | 6-[3-(2-pyridyl)-1- piper...)
Affinity DataIC50: 76.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM299523(US9592235, Example 297 | 6-[3-(2-pyridyl)-1- piper...)
Affinity DataIC50: 76.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent