BDBM299497 N6-benzylpyrido [3,2-d] pyrimidine-4,6- diamine::US9592235, Example 270::US9855269, Compound 117

SMILES Nc1ncnc2ccc(NCc3ccccc3)nc12

InChI Key InChIKey=FIXLQBBKCVJPNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299497   

LigandPNGBDBM299497(US9592235, Example 270 | N6-benzylpyrido [3,2-d] p...)
Affinity DataIC50: 161nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299497(US9592235, Example 270 | N6-benzylpyrido [3,2-d] p...)
Affinity DataIC50: 161nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent