BDBM299494 6-(3-ethoxy- phenyl) quinazolin- 4-amine::US9592235, Example 267::US9855269, Compound 114

SMILES CCOc1cccc(c1)-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=QTEXDXGJZNUEHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299494   

LigandPNGBDBM299494(US9592235, Example 267 | 6-(3-ethoxy- phenyl) quin...)
Affinity DataIC50: 157nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299494(US9592235, Example 267 | 6-(3-ethoxy- phenyl) quin...)
Affinity DataIC50: 157nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent