BDBM299488 1-[3-(4-amino- quinazolin- 6-yl)phenyl]-3- cyclopentyl-urea::US9592235, Example 261::US9855269, Compound 108

SMILES Nc1ncnc2ccc(cc12)-c1cccc(NC(=O)NC2CCCC2)c1

InChI Key InChIKey=WEDOWINRFLQWET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299488   

LigandPNGBDBM299488(US9592235, Example 261 | 1-[3-(4-amino- quinazolin...)
Affinity DataIC50: 136nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299488(US9592235, Example 261 | 1-[3-(4-amino- quinazolin...)
Affinity DataIC50: 136nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent