BDBM299485 6-[3-(6-methyl-2- pyridyl)-1- piperidyl]pyrido [3,2-d]pyrimidin- 4-amine::US9592235, Example 258::US9855269, Compound 105

SMILES Cc1cccc(n1)C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=VNBYTQFVKREWQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299485   

LigandPNGBDBM299485(US9592235, Example 258 | 6-[3-(6-methyl-2- pyridyl...)
Affinity DataIC50: 145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299485(US9592235, Example 258 | 6-[3-(6-methyl-2- pyridyl...)
Affinity DataIC50: 145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent