BDBM299436 N6-[2-(4-fluoro- phenyl)ethyl] pyrido[3,2-d] pyrimidine- 4,6-diamine::US9592235, Example 225::US9855269, Compound 72

SMILES Nc1ncnc2ccc(NCCc3ccc(F)cc3)nc12

InChI Key InChIKey=MAUQWFRCYUDOSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299436   

LigandPNGBDBM299436(US9592235, Example 225 | N6-[2-(4-fluoro- phenyl)e...)
Affinity DataIC50: 70.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
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LigandPNGBDBM299436(US9592235, Example 225 | N6-[2-(4-fluoro- phenyl)e...)
Affinity DataIC50: 70.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent