BDBM299384 6-(5-chloro-2- methyl-phenyl) quinazolin- 4-amine::US9592235, Example 182::US9855269, Compound 26

SMILES Cc1ccc(Cl)cc1-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=UOOIHHNFTZZBJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299384   

LigandPNGBDBM299384(US9592235, Example 182 | 6-(5-chloro-2- methyl-phe...)
Affinity DataIC50: 90.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299384(US9592235, Example 182 | 6-(5-chloro-2- methyl-phe...)
Affinity DataIC50: 90.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent