BDBM299383 6-(3-chloro- phenyl)pyrido [3,2-d] pyrimidin-4- amine::US9592235, Example 181::US9855269, Compound 25

SMILES Nc1ncnc2ccc(nc12)-c1cccc(Cl)c1

InChI Key InChIKey=VDIDQANNEVPPIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299383   

LigandPNGBDBM299383(US9592235, Example 181 | 6-(3-chloro- phenyl)pyrid...)
Affinity DataIC50: 19.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299383(US9592235, Example 181 | 6-(3-chloro- phenyl)pyrid...)
Affinity DataIC50: 19.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent