BDBM29934 piperidine-1-carboxamide, 7h

SMILES [H][C@]1(CCCN(C1)C(=O)N[C@H](CNC)CC1CCCCC1)[C@@H](OCCCOCC)c1ccccc1

InChI Key InChIKey=SXTSVHBFOWFOMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29934   

TargetRenin(Human)
Vitae Pharmaceuticals

LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50: 40nMpH: 7.0 T: 2°CAssay Description:The activity of renin inhibitors in vitro was measured using the FRET assay, which was carried out in flat-bottom white opaque microtiter plates. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2009
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50: 40nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRenin(Human)
Vitae Pharmaceuticals

LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50: 447nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed