BDBM299293 US9593113, Example 57::US9593113, Example 65

SMILES CC(C)Oc1ccc(cn1)-c1ccc2[C@H](c3ccccc3Oc2n1)C(C)(C)C(=O)NC(N)=O

InChI Key InChIKey=JMHPEVLAWDMANV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299293   

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM299293(US9593113, Example 57 | US9593113, Example 65)
Affinity DataKi:  0.5nMAssay Description:Binding Assay (I):In order to assess the affinity of test compounds for the human glucocorticoid receptor, a commercially available kit was used (Glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM299293(US9593113, Example 57 | US9593113, Example 65)
Affinity DataKi:  4.23nMAssay Description:Binding Assay (I):In order to assess the affinity of test compounds for the human glucocorticoid receptor, a commercially available kit was used (Glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
Go to US Patent