BDBM299263 US9593121, I-09::{(1S,2S,4R)-4-[4-(6-chloro-5-fluoro-1H-indol-2-yl)-7H- pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl}methyl

SMILES [CH2][C@H]1C[C@H](C[C@@H]1O)n1ccc2c(ncnc12)-c1cc2cc(F)c(Cl)cc2[nH]1

InChI Key InChIKey=MSFQOFDVWKKCSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299263   

TargetUbiquitin-like modifier-activating enzyme 6(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM299263(US9593121, I-09 | {(1S,2S,4R)-4-[4-(6-chloro-5-flu...)
Affinity DataIC50: 1.03E+3nMAssay Description:The UBA6 enzmatic reaction totals 20 μL and contains 50 mM HEPES (pH 7.5), 0.05% BSA, 0.02% Tween 20, 0.1 mM TCEP, 5 mM MgCl2, 2 μM ATP, 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
Go to US Patent